A Minimal Mathematical Model of Calcium Homeostasis

Spontaneous Calcium Sparks and Calcium Homeostasis in a Minimal Model of Permeabilized Ventricular Myocytes

Many issues remain unresolved concerning how local, subcellular Ca signals interact with bulk cellular concentrations to maintain homeostasis in health and disease. To aid the interpretation of data obtained in quiescent ventricular myocytes, we present a minimal whole cell model that accounts for both localized (subcellular) and global (cellular) aspects of Ca signaling. Using a minimal formul...

ANTICONVULSANT THERAPY-INDUCED ALTERATIONS IN CALCIUM HOMEOSTASIS

35 epileptic patients, aged 10 to 58 years (mean 23), who were taking anticonvulsant drugs were studied. The patients exhibited a 34% reduction in serum calcium levels, a 41 % increase in serum alkaline phosphatase activity and a slight but insignificant decrease in serum phosphate, compared to untreated controls. These changes appear to be related to the anticonvulsant drug taken, in the ...

A Mathematical Model of the Potassium Homeostasis in Saccharomyces cerevisiae

A minimal mathematical model of nonphotochemical quenching of chlorophyll fluorescence

Under natural conditions, plants are exposed to rapidly changing light intensities. To acclimate to such fluctuations, plants have evolved adaptive mechanisms that optimally exploit available light energy and simultaneously minimise damage of the photosynthetic apparatus through excess light. An important mechanism is the dissipation of excess excitation energy as heat which can be measured as ...

Mathematical Model of Blood Calcium Ion Regulation

Group Members Thomas Rosal∗ Ohio State University [email protected] Jonathan Bell Univ of Maryland Baltimore County [email protected] Jana Gevertz The College of New Jersey [email protected] Franziska Hinkelmann Ohio State University [email protected] Glenn Ledder University of Nebraska [email protected] Paul Roberts University of Oxford, UK [email protected] Johanna Stamper U...